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BMCBI
2010
113views more  BMCBI 2010»
15 years 7 months ago
ProbABEL package for genome-wide association analysis of imputed data
Background: Over the last few years, genome-wide association (GWA) studies became a tool of choice for the identification of loci associated with complex traits. Currently, impute...
Yurii S. Aulchenko, Maksim V. Struchalin, Cornelia...
BMCBI
2010
160views more  BMCBI 2010»
15 years 7 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2010
122views more  BMCBI 2010»
15 years 7 months ago
Genome3D: A viewer-model framework for integrating and visualizing multi-scale epigenomic information within a three-dimensional
Background: New technologies are enabling the measurement of many types of genomic and epigenomic information at scales ranging from the atomic to nuclear. Much of this new data i...
Thomas M. Asbury, Matt Mitman, Jijun Tang, W. Jim ...
BMCBI
2010
146views more  BMCBI 2010»
15 years 7 months ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
BMCBI
2007
99views more  BMCBI 2007»
15 years 7 months ago
Statistical significance of cis-regulatory modules
Background: It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding si...
Dustin E. Schones, Andrew D. Smith, Michael Q. Zha...
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