16088 search results - page 2818 / 3218 » A Mean-Variance Optimization algorithm |
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BMCBI
2008
15 years 7 months ago
2008
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
212
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BMCBI
2007
15 years 7 months ago
2007
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
227
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BMCBI
2006
15 years 7 months ago
2006
Background: Bioinformatics applications are now routinely used to analyze large amounts of data. Application development often requires many cycles of optimization, compiling, and...
242
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BMCBI
2006
15 years 7 months ago
2006
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
205
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BMCBI
2006
15 years 7 months ago
2006
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...