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» A Relational Abstraction for Functions
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TRS
2008
15 years 7 months ago
The Neurophysiological Bases of Cognitive Computation Using Rough Set Theory
A popular view is that the brain works in a similar way to a digital computer or a Universal Turing Machine by processing symbols. Psychophysical experiments and our amazing capabi...
Andrzej W. Przybyszewski
BMCBI
2004
111views more  BMCBI 2004»
15 years 7 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
BMCBI
2004
140views more  BMCBI 2004»
15 years 7 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2004
158views more  BMCBI 2004»
15 years 7 months ago
Incremental genetic K-means algorithm and its application in gene expression data analysis
Background: In recent years, clustering algorithms have been effectively applied in molecular biology for gene expression data analysis. With the help of clustering algorithms suc...
Yi Lu, Shiyong Lu, Farshad Fotouhi, Youping Deng, ...
BMCBI
2004
141views more  BMCBI 2004»
15 years 7 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
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