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BMCBI
2005
98views more  BMCBI 2005»
15 years 7 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...
BMCBI
2005
82views more  BMCBI 2005»
15 years 7 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
BMCBI
2005
106views more  BMCBI 2005»
15 years 7 months ago
Thesaurus-based disambiguation of gene symbols
Background: Massive text mining of the biological literature holds great promise of relating disparate information and discovering new knowledge. However, disambiguation of gene s...
Bob J. A. Schijvenaars, Barend Mons, Marc Weeber, ...
BMCBI
2005
100views more  BMCBI 2005»
15 years 7 months ago
Scoredist: A simple and robust protein sequence distance estimator
Background: Distance-based methods are popular for reconstructing evolutionary trees thanks to their speed and generality. A number of methods exist for estimating distances from ...
Erik L. L. Sonnhammer, Volker Hollich
BMCBI
2005
77views more  BMCBI 2005»
15 years 7 months ago
Combining Affymetrix microarray results
Background: As the use of microarray technology becomes more prevalent it is not unusual to find several laboratories employing the same microarray technology to identify genes re...
John R. Stevens, R. W. Doerge
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