76665 search results - page 15188 / 15333 » A proposed |
221
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BCB
2010
15 years 2 months ago
2010
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...
194
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BMCBI
2010
15 years 2 months ago
2010
Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It repre...
219
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BMCBI
2010
15 years 2 months ago
2010
Background: Concomitant with the rise in the popularity of DNA microarrays has been a surge of proposed methods for the analysis of microarray data. Fully controlled "spike-i...
192
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BMCBI
2010
15 years 2 months ago
2010
Background: The brightness of the probe spots on expression microarrays intends to measure the abundance of specific mRNA targets. Probes with runs of at least three guanines (G) ...
230
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BMCBI
2010
15 years 2 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...