77 search results - page 7 / 16 » A structural keystone for drug design |
185
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CORR
2006
Springer
15 years 6 months ago
2006
Springer
The organization and mining of malaria genomic and post-genomic data is important to significantly increase the knowledge of the biology of its causative agents, and is motivated,...
287
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IHI
2012
14 years 2 months ago
2012
Biological network analysis often aims at the target identification problem, which is to predict which molecule to inhibit (or activate) for a disease treatment to achieve optimu...
152
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BMCBI
2008
15 years 6 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
167
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IPPS
2006
IEEE
16 years 21 days ago
2006
IEEE
The prediction of protein 3D structure has become a hot research area in the post-genome era, through which people can understand a protein’s function in health and disease, exp...
195
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BIBE
2004
IEEE
15 years 10 months ago
2004
IEEE
Large-scale biomedical data sets of macromolecular structures such as DNA and proteins describe highly complex biomolecular entities which often consist of thousands of atoms and ...