Interactions that determinecellular fate are exceedingly complex, can take place at different levels of gene regulation and involve a large numberof components(such as genes, prot...
Agent-based simulations are an increasingly popular means of exploring and understanding complex social systems. In order to be useful, these simulations must capture a range of a...
David Scerri, Alexis Drogoul, Sarah L. Hickmott, L...
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...