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224
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ICCAD
1997
IEEE
15 years 11 months ago
1997
IEEE
We introduce a new technique to solve exactly a discrete optimization problem, based on the paradigm of “negative” thinking. The motivation is that when searching the space of...
224
Voted
BMCBI
2010
15 years 7 months ago
2010
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...
206
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BMCBI
2008
15 years 7 months ago
2008
Background: In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differe...
212
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BMCBI
2006
15 years 7 months ago
2006
Background: The identification of biologically interesting genes in a temporal expression profiling dataset is challenging and complicated by high levels of experimental noise. Mo...
224
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BMCBI
2006
15 years 7 months ago
2006
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...