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» Classification of microarray data using gene networks
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CEC
2008
IEEE
16 years 1 months ago
Evolving GeneChip correlation predictors on parallel graphics hardware
—A GPU is used to datamine five million correlations between probes within Affymetrix HG-U133A probesets across 6685 human tissue samples from NCBI’s GEO database. These conco...
William B. Langdon
BMCBI
2010
100views more  BMCBI 2010»
15 years 7 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2008
120views more  BMCBI 2008»
15 years 7 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
GECCO
2005
Springer
180views Optimization» more  GECCO 2005»
16 years 10 days ago
Inference of gene regulatory networks using s-system and differential evolution
In this work we present an improved evolutionary method for inferring S-system model of genetic networks from the time series data of gene expression. We employed Differential Ev...
Nasimul Noman, Hitoshi Iba
BMCBI
2008
126views more  BMCBI 2008»
15 years 7 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li