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230
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BMCBI
2010
15 years 7 months ago
2010
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
224
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BMCBI
2008
15 years 7 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
198
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BMCBI
2007
15 years 7 months ago
2007
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
207
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BMCBI
2010
15 years 7 months ago
2010
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
192
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BMCBI
2008
2008
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
15 years 7 months ago
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...