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BMCBI
2008
190views more  BMCBI 2008»
15 years 7 months ago
Which missing value imputation method to use in expression profiles: a comparative study and two selection schemes
Background: Gene expression data frequently contain missing values, however, most downstream analyses for microarray experiments require complete data. In the literature many meth...
Guy N. Brock, John R. Shaffer, Richard E. Blakesle...
BMCBI
2010
243views more  BMCBI 2010»
15 years 7 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2008
84views more  BMCBI 2008»
15 years 7 months ago
The comparative analysis of statistics, based on the likelihood ratio criterion, in the automated annotation problem
Background: This paper discusses the problem of automated annotation. It is a continuation of the previous work on the A4-algorithm (Adaptive algorithm of automated annotation) de...
Andrey M. Leontovich, Konstantin Y. Tokmachev, Han...
BMCBI
2008
134views more  BMCBI 2008»
15 years 7 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
BMCBI
2008
138views more  BMCBI 2008»
15 years 7 months ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski