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CCE
2005
15 years 6 months ago
Large-scale inference of the transcriptional regulation of Bacillus subtilis
This paper addresses the inference of the transcriptional regulatory network of Bacillus subtilis. Two inference approaches, a linear, additive model and a non-linear power-law mo...
Anshuman Gupta, Jeffrey D. Varner, Costas D. Maran...
BMCBI
2010
139views more  BMCBI 2010»
15 years 7 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
200
Voted
BMCBI
2008
120views more  BMCBI 2008»
15 years 7 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
RECOMB
2007
Springer
16 years 7 months ago
A Heuristic Algorithm for Reconstructing Ancestral Gene Orders with Duplications
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorith...
Jian Ma, Aakrosh Ratan, Louxin Zhang, Webb Miller,...
BIBE
2004
IEEE
15 years 10 months ago
Phylogenetic Reconstruction from Arbitrary Gene-Order Data
Phylogenetic reconstruction from gene-order data has attracted attention from both biologists and computer scientists over the last few years. So far, our software suite GRAPPA is...
Jijun Tang, Bernard M. E. Moret, Liying Cui, Claud...