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BMCBI
2007
157views more  BMCBI 2007»
15 years 7 months ago
A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
Background: The fundamental role that intrinsic stochasticity plays in cellular functions has been shown via numerous computational and experimental studies. In the face of such e...
Asawari Samant, Babatunde A. Ogunnaike, Dionisios ...
SIAMCOMP
2000
90views more  SIAMCOMP 2000»
15 years 6 months ago
From Gene Trees to Species Trees
This paper studies various algorithmic issues in reconstructing a species tree from gene trees under the duplication and the mutation cost model. This is a fundamental problem in c...
Bin Ma, Ming Li, Louxin Zhang
APBC
2004
107views Bioinformatics» more  APBC 2004»
15 years 8 months ago
An Empirical Bayes Adjustment to Multiple p-values for the Detection of Differentially Expressed Genes in Microarray Experiments
In recent microarray experiments thousands of gene expressions are simultaneously tested in comparing samples (e.g., tissue types or experimental conditions). Application of a sta...
Somnath Datta, Susmita Datta
DAM
2008
75views more  DAM 2008»
15 years 7 months ago
Patterns of simple gene assembly in ciliates
The intramolecular model for gene assembly in ciliates considers three operations, ld, hi, and dlad that can assemble any gene pattern through folding and recombination: the molec...
Tero Harju, Ion Petre, Vladimir Rogojin, Grzegorz ...
TCBB
2010
96views more  TCBB 2010»
15 years 1 months ago
A Survey of Spatial Defects in Homo Sapiens Affymetrix GeneChips
Modern biology has moved from a science of individual measurements to a science where data are collected on an industrial scale. Foremost, among the new tools for biochemistry are ...
William B. Langdon, Graham J. G. Upton, Renata da ...