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BMCBI
2010
112views more  BMCBI 2010»
15 years 7 months ago
Computational identification of rare codons of Escherichia coli based on codon pairs preference
Background: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exog...
Xianming Wu, Songfeng Wu, Dong Li, Jiyang Zhang, L...
BMCBI
2010
109views more  BMCBI 2010»
15 years 7 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
RECOMB
2002
Springer
16 years 7 months ago
Discovering local structure in gene expression data: the order-preserving submatrix problem
This paper concerns the discovery of patterns in gene expression matrices, in which each element gives the expression level of a given gene in a given experiment. Most existing me...
Amir Ben-Dor, Benny Chor, Richard M. Karp, Zohar Y...
ISMB
2000
15 years 8 months ago
Analysis of Gene Expression Microarrays for Phenotype Classification
Several microarray technologies that monitor the level of expression of a large number of genes have recently emerged. Given DNA-microarray data for a set of cells characterized b...
Andrea Califano, Gustavo Stolovitzky, Yuhai Tu