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BMCBI
2008
153views more  BMCBI 2008»
15 years 7 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
BMCBI
2006
110views more  BMCBI 2006»
15 years 7 months ago
Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...
RAS
2008
108views more  RAS 2008»
15 years 6 months ago
Towards long-lived robot genes
Robot projects are often evolutionary dead ends, with the software and hardware they produce disappearing without trace afterwards. Common causes include dependencies on uncommon ...
Paul M. Fitzpatrick, Giorgio Metta, Lorenzo Natale
BMCBI
2007
166views more  BMCBI 2007»
15 years 7 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
SDM
2007
SIAM
143views Data Mining» more  SDM 2007»
15 years 8 months ago
Less is More: Compact Matrix Decomposition for Large Sparse Graphs
Given a large sparse graph, how can we find patterns and anomalies? Several important applications can be modeled as large sparse graphs, e.g., network traffic monitoring, resea...
Jimeng Sun, Yinglian Xie, Hui Zhang, Christos Falo...