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» Computation in Gene Networks
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RECOMB
2010
Springer
15 years 9 months ago
Subnetwork State Functions Define Dysregulated Subnetworks in Cancer
Abstract. Emerging research demonstrates the potential of proteinprotein interaction (PPI) networks in uncovering the mechanistic bases of cancers, through identification of intera...
Salim A. Chowdhury, Rod K. Nibbe, Mark R. Chance, ...
RECOMB
2005
Springer
16 years 7 months ago
Modeling the Combinatorial Functions of Multiple Transcription Factors
A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...
Chen-Hsiang Yeang, Tommi Jaakkola
EVOW
2005
Springer
16 years 22 days ago
Evolutionary Biclustering of Microarray Data
In this work, we address the biclustering of gene expression data with evolutionary computation, which has been proven to have excellent performance on complex problems. In express...
Jesús S. Aguilar-Ruiz, Federico Divina
JCB
2008
102views more  JCB 2008»
15 years 7 months ago
DUPCAR: Reconstructing Contiguous Ancestral Regions with Duplications
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
Jian Ma, Aakrosh Ratan, Brian J. Raney, Bernard B....
BMCBI
2010
153views more  BMCBI 2010»
15 years 7 months ago
VITCOMIC: visualization tool for taxonomic compositions of microbial communities based on 16S rRNA gene sequences
Background: Understanding the community structure of microbes is typically accomplished by sequencing 16S ribosomal RNA (16S rRNA) genes. These community data can be represented b...
Hiroshi Mori, Fumito Maruyama, Ken Kurokawa