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BMCBI
2006
119views more  BMCBI 2006»
15 years 7 months ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
BMCBI
2006
131views more  BMCBI 2006»
15 years 7 months ago
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...
Allan A. Sioson, Shrinivasrao P. Mane, Pinghua Li,...
GECCO
2005
Springer
186views Optimization» more  GECCO 2005»
16 years 22 days ago
Subproblem optimization by gene correlation with singular value decomposition
Several ways of using singular value decomposition (SVD), a linear algebra technique typically used for information retrieval, to decompose problems into subproblems are investiga...
Jacob G. Martin
BMCBI
2008
130views more  BMCBI 2008»
15 years 7 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen
BMCBI
2007
144views more  BMCBI 2007»
15 years 7 months ago
Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data
Background: In practice many biological time series measurements, including gene microarrays, are conducted at time points that seem to be interesting in the biologist's opin...
Miika Ahdesmäki, Harri Lähdesmäki, ...