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HYBRID
2001
Springer
15 years 11 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
JBI
2002
15 years 7 months ago
Revising regulatory networks: from expression data to linear causal models
Discovering the complex regulatory networks that govern mRNA expression is an important but difficult problem. Many current approaches use only expression data from microarrays to...
Stephen D. Bay, Jeff Shrager, Andrew Pohorille, Pa...
EJASP
2010
132views more  EJASP 2010»
15 years 2 months ago
Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor mod...
Jia Meng, Jianqiu Zhang, Yuan (Alan) Qi, Yidong Ch...
HPDC
1993
IEEE
15 years 11 months ago
An Analysis of Distributed Computing Software and Hardware for Applications in Computational Physics
We have implemented a set of computational physics codes on a network of IBM RS/6000 workstations used as a distributed parallel computer. We compare the performance of the codes ...
Paul D. Coddington
CGF
2008
151views more  CGF 2008»
15 years 6 months ago
Navigation and Exploration of Interconnected Pathways
Visualizing pathways, i. e. models of cellular functional networks, is a challenging task in computer assisted biomedicine. Pathways are represented as large collections of interw...
Marc Streit, Michael Kalkusch, Karl Kashofer, Diet...