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» Computer algebra in systems biology
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SAC
2003
ACM
16 years 12 days ago
Similar_Join: Extending DBMS with a Bio-specific Operator
Existing sequence comparison software applications lack automation, abstraction, performance, and flexibility. Users need a new way of studying and applying sequence comparisons i...
Jake Yue Chen, John V. Carlis
CIBCB
2007
IEEE
15 years 11 months ago
Genetic Regulatory Network Modeling Using Network Component Analysis and Fuzzy Clustering
Gene regulatory network model is the most widely used mechanism to model and predict the behavior of living organisms. Network Component Analysis (NCA) as an emerging issue for unc...
Fatemeh Bakouie, Mohammad Hassan Moradi
ISMB
1998
15 years 8 months ago
Modeling Protein Homopolymeric Repeats: Possible Polyglutamine Structural Motifs for Huntington's Disease
Wedescribe a prototype system (Poly-X) for assisting an expert user in modelingprotein repeats. Poly-X reduces the large numberof degrees of freedomrequired to specify a protein m...
Richard H. Lathrop, Malcolm S. Casale, Douglas J. ...
ISMB
1993
15 years 8 months ago
Knowledge-Based Generation of Machine-Learning Experiments: Learning with DNA Crystallography Data
Thoughit has been possible in the past to learn to predict DNAhydration patterns from crystallographic data, there is ambiguity in the choice of training data (both in terms of th...
Dawn M. Cohen, Casimir A. Kulikowski, Helen Berman
CORR
2010
Springer
174views Education» more  CORR 2010»
15 years 7 months ago
Hybrid Numerical Solution of the Chemical Master Equation
We present a numerical approximation technique for the analysis of continuous-time Markov chains that describe networks of biochemical reactions and play an important role in the ...
Thomas A. Henzinger, Maria Mateescu, Linar Mikeev,...