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ALMOB
2008
81views more  ALMOB 2008»
15 years 7 months ago
Stability of multiple alignments and phylogenetic trees: an analysis of ABC-transporter proteins family
Background: Sequence-based phylogeny reconstruction is a fundamental task in Bioinformatics. Practically all methods for phylogeny reconstruction are based on multiple alignments....
Holger Wagner, Burkhard Morgenstern, Andreas W. M....
BIOINFORMATICS
2007
123views more  BIOINFORMATICS 2007»
15 years 7 months ago
A comparative genome approach to marker ordering
Motivation: Genome maps are fundamental to the study of an organism and essential in the process of genome sequencing which in turn provides the ultimate map of the genome. The in...
Thomas Faraut, Simon de Givry, Patrick Chabrier, T...
BMCBI
2010
107views more  BMCBI 2010»
15 years 7 months ago
Semantic annotation of morphological descriptions: an overall strategy
Background: Large volumes of morphological descriptions of whole organisms have been created as print or electronic text in a human-readable format. Converting the descriptions in...
Hong Cui
BMCBI
2010
121views more  BMCBI 2010»
15 years 7 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
BMCBI
2010
132views more  BMCBI 2010»
15 years 7 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...