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BMCBI
2010
124views more  BMCBI 2010»
15 years 7 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
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BMCBI
2008
105views more  BMCBI 2008»
15 years 7 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
FUIN
2008
119views more  FUIN 2008»
15 years 7 months ago
Modeling Communication with Synchronized Environments
A deterministic behavior of systems composed of several modules is a desirable design goal. Assembling a complex system from components requires also a high degree of re-usability....
Tiberiu Seceleanu, Axel Jantsch
BMCBI
2007
186views more  BMCBI 2007»
15 years 7 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
IJHPCA
2008
131views more  IJHPCA 2008»
15 years 7 months ago
De Novo Ultrascale Atomistic Simulations On High-End Parallel Supercomputers
We present a de novo hierarchical simulation framework for first-principles based predictive simulations of materials and their validation on high-end parallel supercomputers and ...
Aiichiro Nakano, Rajiv K. Kalia, Ken-ichi Nomura, ...