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BMCBI
2007
99views more  BMCBI 2007»
15 years 7 months ago
Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Ki
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...
Jenny Gu, Philip E. Bourne
BMCBI
2008
98views more  BMCBI 2008»
15 years 7 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
BMCBI
2006
109views more  BMCBI 2006»
15 years 7 months ago
iHOPerator: user-scripting a personalized bioinformatics Web, starting with the iHOP website
Background: User-scripts are programs stored in Web browsers that can manipulate the content of websites prior to display in the browser. They provide a novel mechanism by which u...
Benjamin M. Good, Edward A. Kawas, Byron Yu-Lin Ku...
BMCBI
2006
110views more  BMCBI 2006»
15 years 7 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
IDA
2006
Springer
15 years 7 months ago
Backward chaining rule induction
Exploring the vast number of possible feature interactions in domains such as gene expression microarray data is an onerous task. We describe Backward-Chaining Rule Induction (BCR...
Douglas H. Fisher, Mary E. Edgerton, Zhihua Chen, ...