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BMCBI
2008
126views more  BMCBI 2008»
15 years 7 months ago
Methods for evaluating gene expression from Affymetrix microarray datasets
Background: Affymetrix high density oligonucleotide expression arrays are widely used across all fields of biological research for measuring genome-wide gene expression. An import...
Ning Jiang, Lindsey J. Leach, Xiaohua Hu, Elena Po...
BMCBI
2008
129views more  BMCBI 2008»
15 years 7 months ago
Gene set enrichment analysis for non-monotone association and multiple experimental categories
Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
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BMCBI
2008
115views more  BMCBI 2008»
15 years 7 months ago
Improving peptide-MHC class I binding prediction for unbalanced datasets
Background: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such bin...
Ana Paula Sales, Georgia D. Tomaras, Thomas B. Kep...
BMCBI
2008
96views more  BMCBI 2008»
15 years 7 months ago
Mapping proteins to disease terminologies: from UniProt to MeSH
Background: Although the UniProt KnowledgeBase is not a medical-oriented database, it contains information on more than 2,000 human proteins involved in pathologies. However, thes...
Anaïs Mottaz, Yum Lina Yip, Patrick Ruch, Ann...
CGF
2008
118views more  CGF 2008»
15 years 7 months ago
Exploratory Visualization of Animal Kinematics Using Instantaneous Helical Axes
We present novel visual and interactive techniques for exploratory visualization of animal kinematics using instantaneous helical axes (IHAs). The helical axis has been used in or...
Daniel F. Keefe, Trevor M. O'Brien, D. B. Baier, S...