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BMCBI
2006
114views more  BMCBI 2006»
15 years 7 months ago
A high level interface to SCOP and ASTRAL implemented in Python
Background: Benchmarking algorithms in structural bioinformatics often involves the construction of datasets of proteins with given sequence and structural properties. The SCOP da...
James A. Casbon, Gavin E. Crooks, Mansoor A. S. Sa...
BMCBI
2006
165views more  BMCBI 2006»
15 years 7 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2006
91views more  BMCBI 2006»
15 years 7 months ago
Empirical study of supervised gene screening
Background: Microarray studies provide a way of linking variations of phenotypes with their genetic causations. Constructing predictive models using high dimensional microarray me...
Shuangge Ma
BMCBI
2006
115views more  BMCBI 2006»
15 years 7 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan
COR
2006
97views more  COR 2006»
15 years 7 months ago
Evaluating the performance of cost-based discretization versus entropy- and error-based discretization
Discretization is defined as the process that divides continuous numeric values into intervals of discrete categorical values. In this article, the concept of cost-based discretiz...
Davy Janssens, Tom Brijs, Koen Vanhoof, Geert Wets