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BMCBI
2010
154views more  BMCBI 2010»
15 years 7 months ago
An algorithm for automated closure during assembly
Background: Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can invol...
Sergey Koren, Jason R. Miller, Brian Walenz, Grang...
BMCBI
2008
130views more  BMCBI 2008»
15 years 7 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2007
131views more  BMCBI 2007»
15 years 7 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
BMCBI
2007
111views more  BMCBI 2007»
15 years 7 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...
BMCBI
2007
109views more  BMCBI 2007»
15 years 7 months ago
Seahawk: moving beyond HTML in Web-based bioinformatics analysis
Background: Traditional HTML interfaces for input to and output from Bioinformatics analysis on the Web are highly variable in style, content and data formats. Combining multiple ...
Paul M. K. Gordon, Christoph W. Sensen
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