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BMCBI
2008
97views more  BMCBI 2008»
15 years 7 months ago
Interrogating domain-domain interactions with parsimony based approaches
Background: The identification and characterization of interacting domain pairs is an important step towards understanding protein interactions. In the last few years, several met...
Katia S. Guimarães, Teresa M. Przytycka
BMCBI
2008
102views more  BMCBI 2008»
15 years 7 months ago
PhyloNet: a software package for analyzing and reconstructing reticulate evolutionary relationships
Background: Phylogenies, i.e., the evolutionary histories of groups of taxa, play a major role in representing the interrelationships among biological entities. Many software tool...
Cuong Than, Derek A. Ruths, Luay Nakhleh
BMCBI
2008
80views more  BMCBI 2008»
15 years 7 months ago
Towards an automatic classification of protein structural domains based on structural similarity
Background: Formal classification of a large collection of protein structures aids the understanding of evolutionary relationships among them. Classifications involving manual ste...
Vichetra Sam, Chin-Hsien Tai, Jean Garnier, Jean-F...
BMCBI
2008
83views more  BMCBI 2008»
15 years 7 months ago
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells
Background: Microarray technology has unveiled transcriptomic differences among tumors of various phenotypes, and, especially, brought great progress in molecular understanding of...
Atsushi Niida, Andrew D. Smith, Seiya Imoto, Shuic...
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BMCBI
2008
116views more  BMCBI 2008»
15 years 7 months ago
Clustering exact matches of pairwise sequence alignments by weighted linear regression
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
Alvaro J. González, Li Liao
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