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221
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BMCBI
2008
15 years 7 months ago
2008
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
251
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BMCBI
2008
15 years 7 months ago
2008
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
196
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BMCBI
2008
15 years 7 months ago
2008
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...
221
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BMCBI
2008
15 years 7 months ago
2008
Background: In DNA microarray gene expression profiling studies, a fundamental task is to extract statistically significant genes that meet certain research hypothesis. Currently,...
239
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BMCBI
2008
15 years 7 months ago
2008
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...