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BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
15 years 7 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
BIOINFORMATICS
2006
134views more  BIOINFORMATICS 2006»
15 years 7 months ago
HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies
The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are no...
Mahender Kumar Singh, Shilpy Srivastava, G. P. S. ...
FOCM
2008
100views more  FOCM 2008»
15 years 7 months ago
A Unifying Local Convergence Result for Newton's Method in Riemannian Manifolds
We consider the problem of finding a singularity of a differentiable vector field X defined on a complete Riemannian manifold. We prove a unified result for the existence and local...
Felipe Alvarez, Jérôme Bolte, Julien ...
FUIN
2008
119views more  FUIN 2008»
15 years 7 months ago
Modeling Communication with Synchronized Environments
A deterministic behavior of systems composed of several modules is a desirable design goal. Assembling a complex system from components requires also a high degree of re-usability....
Tiberiu Seceleanu, Axel Jantsch
BMCBI
2006
159views more  BMCBI 2006»
15 years 7 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
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