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200
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BMCBI
2006
15 years 7 months ago
2006
Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detectio...
218
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BMCBI
2006
15 years 7 months ago
2006
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
213
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BMCBI
2006
15 years 7 months ago
2006
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
218
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BMCBI
2006
15 years 7 months ago
2006
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
208
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BMCBI
2006
15 years 7 months ago
2006
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...