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» Efficient protein alignment algorithm for protein search
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ISMB
1996
15 years 8 months ago
The Megaprior Heuristic for Discovering Protein Sequence Patterns
Several computeralgorithms for discovering patterns in groups of protein sequences are in use that are basedon fitting the parametersof a statistical model to a group of related s...
Timothy L. Bailey, Michael Gribskov
TIT
2010
170views Education» more  TIT 2010»
15 years 1 months ago
Belief propagation estimation of protein and domain interactions using the sum-product algorithm
We present a novel framework to estimate protein-protein (PPI) and domain-domain (DDI) interactions based on a belief propagation estimation method that efficiently computes inter...
Faruck Morcos, Marcin Sikora, Mark S. Alber, Dale ...
BMCBI
2010
160views more  BMCBI 2010»
15 years 6 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BIOCOMP
2006
15 years 8 months ago
Learning Genetic and Gene Bayesian Networks with Hidden Variables: Bilayer Verification Algorithm
To improve the recovery of gene-gene and marker-gene (eQTL) interaction networks from microarray and genetic data, we propose a new procedure for learning Bayesian networks. This a...
Jason E. Aten
RIVF
2008
15 years 8 months ago
Speeding up subset seed algorithm for intensive protein sequence comparison
Abstract--Sequence similarity search is a common and repeated task in molecular biology. The rapid growth of genomic databases leads to the need of speeding up the treatment of thi...
Van Hoa Nguyen, Dominique Lavenier