The tridimensional structure of a protein is constrained or stabilized by some local interactions between distant residues of the protein, such as disulfide bonds, electrostatic i...
With the popularity of efficient multi-objective evolutionary optimization (EMO) techniques and the need for such problem-solving activities in practice, EMO methodologies and EMO ...
Numerical design optimization algorithms are highly sensitive to the particular formulation of the optimization problems they are given. The formulation of the search space, the o...
Thomas Ellman, John Keane, Takahiro Murata, Mark S...
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo
Background: Application of phenetic methods to gene expression analysis proved to be a successful approach. Visualizing the results in a 3-dimentional space may further enhance th...