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BMCBI
2008
129views more  BMCBI 2008»
15 years 7 months ago
Prediction of the outcome of preoperative chemotherapy in breast cancer using DNA probes that provide information on both comple
Background: DNA microarray technology has emerged as a major tool for exploring cancer biology and solving clinical issues. Predicting a patient's response to chemotherapy is...
René Natowicz, Roberto Incitti, Euler Guima...
BMCBI
2008
211views more  BMCBI 2008»
15 years 7 months ago
CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Svetlin Manavski, Giorgio Valle
BMCBI
2006
98views more  BMCBI 2006»
15 years 7 months ago
In search of functional association from time-series microarray data based on the change trend and level of gene expression
Background: The increasing availability of time-series expression data opens up new possibilities to study functional linkages of genes. Present methods used to infer functional l...
Feng He, An-Ping Zeng
BMCBI
2006
195views more  BMCBI 2006»
15 years 7 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona
BMCBI
2006
91views more  BMCBI 2006»
15 years 7 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...