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» From Cardiac Cells to Genetic Regulatory Networks
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EH
2004
IEEE
106views Hardware» more  EH 2004»
15 years 10 months ago
How to Evolve the Head-Tail Pattern from Reaction-Diffusion Systems
The possible application of evolving artificial embryos to build functional machinery is a promising area of research. Unfortunately, there are still many fundamental problems to ...
Felix Streichert, Christian Spieth, Holger Ulmer, ...
GECCO
2007
Springer
131views Optimization» more  GECCO 2007»
16 years 26 days ago
Using feedback to regulate gene expression in a developmental control architecture
We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developme...
Kester Clegg, Susan Stepney, Tim Clarke
BMCBI
2006
133views more  BMCBI 2006»
15 years 6 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
BMCBI
2006
202views more  BMCBI 2006»
15 years 6 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
BMCBI
2010
160views more  BMCBI 2010»
15 years 6 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian