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BMCBI
2008
136views more  BMCBI 2008»
15 years 7 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash
BMCBI
2006
117views more  BMCBI 2006»
15 years 7 months ago
A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kineti
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
I. Emrah Nikerel, Wouter A. van Winden, Walter M. ...
BMCBI
2006
113views more  BMCBI 2006»
15 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
IOR
2008
91views more  IOR 2008»
15 years 7 months ago
A Randomized Quasi-Monte Carlo Simulation Method for Markov Chains
We introduce and study a randomized quasi-Monte Carlo method for estimating the state distribution at each step of a Markov chain. The number of steps in the chain can be random an...
Pierre L'Ecuyer, Christian Lécot, Bruno Tuf...
JUCS
2006
141views more  JUCS 2006»
15 years 7 months ago
Constraint Based Methods for Biological Sequence Analysis
: The need for processing biological information is rapidly growing, owing to the masses of new information in digital form being produced at this time. Old methodologies for proce...
Maryam Bavarian, Verónica Dahl