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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
15 years 6 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2006
144views more  BMCBI 2006»
15 years 6 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
CPM
2005
Springer
97views Combinatorics» more  CPM 2005»
16 years 7 days ago
On the Complexity of Sparse Exon Assembly
Gene structure prediction is one of the most important problems in computational molecular biology. It involves two steps: the first is finding the evidence (e.g. predicting spl...
Carmel Kent, Gad M. Landau, Michal Ziv-Ukelson
CCCG
2009
15 years 7 months ago
Defining and computing accessibility radius
In structural molecular biology software, the accessibility of an atom in a molecule to a ball representing solvent is either computed slowly by building a solventaccessible surfa...
Vishal Verma, Jack Snoeyink
BIB
2010
147views more  BIB 2010»
15 years 6 months ago
Toward the dynamic interactome: it's about time
Dynamic molecular interactions play a central role in regulating the functioning of cells and organisms.The availability of experimentally determined large-scale cellular networks...
Teresa M. Przytycka, Mona Singh, Donna K. Slonim