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BMCBI
2010
161views more  BMCBI 2010»
15 years 7 months ago
BPDA - A Bayesian peptide detection algorithm for mass spectrometry
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Youting Sun, Jianqiu Zhang, Ulisses Braga-Neto, Ed...
BMCBI
2008
97views more  BMCBI 2008»
15 years 7 months ago
Comparison study on k-word statistical measures for protein: From sequence to 'sequence space'
Background: Many proposed statistical measures can efficiently compare protein sequence to further infer protein structure, function and evolutionary information. They share the s...
Qi Dai, Tian-Ming Wang
BMCBI
2008
122views more  BMCBI 2008»
15 years 7 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
BMCBI
2008
102views more  BMCBI 2008»
15 years 7 months ago
Response projected clustering for direct association with physiological and clinical response data
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
Sung-Gon Yi, Taesung Park, Jae K. Lee
BMCBI
2008
136views more  BMCBI 2008»
15 years 7 months ago
Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models
Background: When predictive survival models are built from high-dimensional data, there are often additional covariates, such as clinical scores, that by all means have to be incl...
Harald Binder, Martin Schumacher
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