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213
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BMCBI
2010
15 years 7 months ago
2010
Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
184
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BMCBI
2008
15 years 7 months ago
2008
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
174
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BMCBI
2008
15 years 7 months ago
2008
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties with potential implications f...
198
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BMCBI
2006
15 years 6 months ago
2006
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
150
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BMCBI
2006
15 years 6 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...