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BMCBI
2008
136views more  BMCBI 2008»
15 years 7 months ago
Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models
Background: When predictive survival models are built from high-dimensional data, there are often additional covariates, such as clinical scores, that by all means have to be incl...
Harald Binder, Martin Schumacher
BMCBI
2008
77views more  BMCBI 2008»
15 years 7 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2008
120views more  BMCBI 2008»
15 years 7 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
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BMCBI
2008
141views more  BMCBI 2008»
15 years 7 months ago
Ontology-guided data preparation for discovering genotype-phenotype relationships
Complexity of post-genomic data and multiplicity of mining strategies are two limits to Knowledge Discovery in Databases (KDD) in life sciences. Because they provide a semantic fr...
Adrien Coulet, Malika Smaïl-Tabbone, Pascale ...
CONCURRENCY
2010
130views more  CONCURRENCY 2010»
15 years 7 months ago
Enabling high-speed asynchronous data extraction and transfer using DART
As the complexity and scale of current scientific and engineering applications grow, managing and transporting the large amounts of data they generate is quickly becoming a signif...
Ciprian Docan, Manish Parashar, Scott Klasky