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BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
15 years 7 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
BMCBI
2010
129views more  BMCBI 2010»
15 years 7 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
208
Voted
BMCBI
2011
14 years 10 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
195
Voted
ICA
2004
Springer
16 years 11 days ago
Blind Maximum Likelihood Separation of a Linear-Quadratic Mixture
Abstract. We proposed recently a new method for separating linearquadratic mixtures of independent real sources, based on parametric identification of a recurrent separating struc...
Shahram Hosseini, Yannick Deville
BMCBI
2007
128views more  BMCBI 2007»
15 years 7 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini