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222
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BMCBI
2010
15 years 7 months ago
2010
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
205
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BMCBI
2007
15 years 7 months ago
2007
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
170
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BMCBI
2008
15 years 7 months ago
2008
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
159
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BMCBI
2007
15 years 7 months ago
2007
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
224
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BMCBI
2007
2007
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
15 years 7 months ago
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...