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BMCBI
2010
165views more  BMCBI 2010»
15 years 7 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
BMCBI
2010
109views more  BMCBI 2010»
15 years 7 months ago
Structural alphabets derived from attractors in conformational space
Background: The hierarchical and partially redundant nature of protein structures justifies the definition of frequently occurring conformations of short fragments as `states'...
Alessandro Pandini, Arianna Fornili, Jens Kleinjun...
BMCBI
2010
123views more  BMCBI 2010»
15 years 7 months ago
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context
Background: Different microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little ov...
Gad Abraham, Adam Kowalczyk, Sherene Loi, Izhak Ha...
BMCBI
2010
136views more  BMCBI 2010»
15 years 7 months ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
BMCBI
2010
113views more  BMCBI 2010»
15 years 7 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
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