This paper introduces GLOCSA as a new scoring function to rate multiple sequence alignments. It is intended to be simple, considering the whole alignment at once and reflecting t...
Dynamic molecular interactions play a central role in regulating the functioning of cells and organisms.The availability of experimentally determined large-scale cellular networks...
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
Multiple sequence alignment (MSA) and phylogenetic tree reconstruction are one of the most important problems in the computational biology. While both these problems are of great ...
: The increasing availability of protein-protein interaction graphs (PPI) requires new efficient tools capable of extracting valuable biological knowledge from these networks. Amon...