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RECOMB
2008
Springer
16 years 8 months ago
Automatic Parameter Learning for Multiple Network Alignment
We developed Gr?mlin 2.0, a new multiple network aligner with (1) a novel scoring function that can use arbitrary features of a multiple network alignment, such as protein deletion...
Jason Flannick, Antal F. Novak, Chuong B. Do, Bala...
RECOMB
2008
Springer
16 years 8 months ago
Limitations of Pseudogenes in Identifying Gene Losses
The loss of previously established genes has been proposed as a major force in evolutionary change. While the sequencing of many new species offers the opportunity to identify case...
James C. Costello, Mira V. Han, Matthew W. Hahn
RECOMB
2007
Springer
16 years 8 months ago
An Efficient Method for Dynamic Analysis of Gene Regulatory Networks and in silico Gene Perturbation Experiments
With the increasing availability of experimental data on gene-gene and protein-protein interactions, modeling of gene regulatory networks has gained a special attention lately. To ...
Abhishek Garg, Ioannis Xenarios, Luis Mendoza, Gio...
RECOMB
2007
Springer
16 years 8 months ago
Rearrangements in Genomes with Centromeres Part I: Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromere...
Michal Ozery-Flato, Ron Shamir
RECOMB
2006
Springer
16 years 8 months ago
Inferring Positional Homologs with Common Intervals of Sequences
Inferring orthologous and paralogous genes is an important problem in whole genomes comparisons, both for functional or evolutionary studies. In this paper, we introduce a new appr...
Guillaume Blin, Annie Chateau, Cedric Chauve, Yann...