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» New architectures for a new biology
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RECOMB
2002
Springer
16 years 8 months ago
Deconvolving sequence variation in mixed DNA populations
We present an original approach to identifying sequence variants in a mixed DNA population from sequence trace data. The heart of the method is based on parsimony: given a wildtyp...
Andy Wildenberg, Steven Skiena, Pavel Sumazin
CIBCB
2008
IEEE
16 years 2 months ago
Very large scale ReliefF for genome-wide association analysis
— The genetic causes of many monogenic diseases have already been discovered. However, most common diseases are actually the result of complex nonlinear interactions between mult...
Margaret J. Eppstein, Paul Haake
241
Voted
ECCB
2008
IEEE
16 years 2 months ago
SIRENE: supervised inference of regulatory networks
Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in ...
Fantine Mordelet, Jean-Philippe Vert
CSB
2005
IEEE
206views Bioinformatics» more  CSB 2005»
16 years 1 months ago
Bioinformatic Insights from Metagenomics through Visualization
Cutting-edge biological and bioinformatics research seeks a systems perspective through the analysis of multiple types of high-throughput and other experimental data for the same ...
Susan L. Havre, Bobbie-Jo M. Webb-Robertson, Anuj ...
187
Voted
GCB
2005
Springer
117views Biometrics» more  GCB 2005»
16 years 1 months ago
Generation of 3D templates of active sites of proteins with rigid prosthetic groups
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
Jean-Christophe Nebel