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BMCBI
2006
144views more  BMCBI 2006»
15 years 7 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
BMCBI
2006
116views more  BMCBI 2006»
15 years 7 months ago
Integrative missing value estimation for microarray data
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
Jianjun Hu, Haifeng Li, Michael S. Waterman, Xiang...
DATAMINE
2006
164views more  DATAMINE 2006»
15 years 6 months ago
Fast Distributed Outlier Detection in Mixed-Attribute Data Sets
Efficiently detecting outliers or anomalies is an important problem in many areas of science, medicine and information technology. Applications range from data cleaning to clinica...
Matthew Eric Otey, Amol Ghoting, Srinivasan Partha...
BMCBI
2007
157views more  BMCBI 2007»
15 years 6 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
BMCBI
2007
141views more  BMCBI 2007»
15 years 6 months ago
A novel approach to detect hot-spots in large-scale multivariate data
Background: Progressive advances in the measurement of complex multifactorial components of biological processes involving both spatial and temporal domains have made it difficult...
Jianhua Wu, Keith M. Kendrick, Jianfeng Feng
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