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BMCBI
2005
103views more  BMCBI 2005»
15 years 7 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe
BMCBI
2005
201views more  BMCBI 2005»
15 years 7 months ago
A comparative study of discriminating human heart failure etiology using gene expression profiles
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
Xiaohong Huang, Wei Pan, Suzanne Grindle, Xinqiang...
BMCBI
2005
127views more  BMCBI 2005»
15 years 7 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
BMCBI
2004
98views more  BMCBI 2004»
15 years 7 months ago
Incidence of "quasi-ditags" in catalogs generated by Serial Analysis of Gene Expression (SAGE)
Background: Serial Analysis of Gene Expression (SAGE) is a functional genomic technique that quantitatively analyzes the cellular transcriptome. The analysis of SAGE libraries rel...
Sergey V. Anisimov, Alexei A. Sharov
BMCBI
2004
135views more  BMCBI 2004»
15 years 7 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...