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BMCBI
2010
116views more  BMCBI 2010»
15 years 7 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2010
106views more  BMCBI 2010»
15 years 7 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li
BMCBI
2008
150views more  BMCBI 2008»
15 years 7 months ago
13C labeling experiments at metabolic nonstationary conditions: An exploratory study
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
Sebastian Aljoscha Wahl, Katharina Nöh, Wolfg...
BMCBI
2008
168views more  BMCBI 2008»
15 years 7 months ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze
DATAMINE
2008
143views more  DATAMINE 2008»
15 years 7 months ago
Automatically countering imbalance and its empirical relationship to cost
Learning from imbalanced datasets presents a convoluted problem both from the modeling and cost standpoints. In particular, when a class is of great interest but occurs relatively...
Nitesh V. Chawla, David A. Cieslak, Lawrence O. Ha...
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