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BMCBI
2010
158views more  BMCBI 2010»
15 years 7 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel
BMCBI
2007
179views more  BMCBI 2007»
15 years 7 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
BMCBI
2010
149views more  BMCBI 2010»
15 years 7 months ago
KID - an algorithm for fast and efficient text mining used to automatically generate a database containing kinetic information o
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
Stephanie Heinen, Bernhard Thielen, Dietmar Schomb...
BMCBI
2007
135views more  BMCBI 2007»
15 years 7 months ago
Measuring similarities between gene expression profiles through new data transformations
Background: Clustering methods are widely used on gene expression data to categorize genes with similar expression profiles. Finding an appropriate (dis)similarity measure is crit...
Kyungpil Kim, Shibo Zhang, Keni Jiang, Li Cai, In-...
BMCBI
2007
101views more  BMCBI 2007»
15 years 7 months ago
Statistical validation of megavariate effects in ASCA
Background: Innovative extensions of (M) ANOVA gain common ground for the analysis of designed metabolomics experiments. ASCA is such a multivariate analysis method; it has succes...
Daniel J. Vis, Johan A. Westerhuis, Age K. Smilde,...
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