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» On the Complexity of Real Functions
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BMCBI
2008
82views more  BMCBI 2008»
15 years 7 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey
BMCBI
2007
157views more  BMCBI 2007»
15 years 7 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
222
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BMCBI
2006
143views more  BMCBI 2006»
15 years 7 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
BMCBI
2006
175views more  BMCBI 2006»
15 years 7 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
187
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IJNSEC
2008
96views more  IJNSEC 2008»
15 years 7 months ago
Eliminating Quadratic Slowdown in Two-Prime RSA Function Sharing
The nature of the RSA public modulus N as a composite of at least two secret large primes was always considered as a major obstacle facing the RSA function sharing without the hel...
Maged Hamada Ibrahim