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BMCBI
2008
129views more  BMCBI 2008»
15 years 7 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2007
166views more  BMCBI 2007»
15 years 7 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2008
170views more  BMCBI 2008»
15 years 7 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
COR
2008
122views more  COR 2008»
15 years 7 months ago
First steps to the runtime complexity analysis of ant colony optimization
: The paper presents results on the runtime complexity of two ant colony optimization (ACO) algorithms: Ant System, the oldest ACO variant, and GBAS, the first ACO variant for whic...
Walter J. Gutjahr
GPEM
2008
98views more  GPEM 2008»
15 years 7 months ago
Sporadic model building for efficiency enhancement of the hierarchical BOA
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
Martin Pelikan, Kumara Sastry, David E. Goldberg
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